There are very few things that scare grown men into tears; hair loss is one of them. However, thanks to a non-invasive, low-cost hair-growth-stimulating technology developed by engineers at the University of Wisconsin-Madison, reversing baldness could someday become a reality.
“I think this will be a very practical solution to hair regeneration,” says Xudong Wang, a professor of materials science and engineering at UW-Madison.
Wang and colleagues published a description of the technology in the journal ACS Nano.
Based on devices that gather energy from a body’s day-to-day motion, the hair-growth technology will stimulate the skin with gentle, low-frequency electric pulses, which coax dormant follicles to reactivate hair production.
These devices won’t cause hair follicles to sprout anew in smooth skin. Instead, they would reactivate hair-producing structures that have gone dormant. That means they could be used as an intervention for people in the early stages of pattern baldness, but they wouldn’t bestow cascading tresses to someone who has been as bald as a billiard ball for several years.
Because the devices are powered by the movement of the wearer, they don’t require a bulky battery pack or complicated electronics. In fact, they’re so low-profile that they could be discreetly worn underneath the crown of an everyday baseball cap.
Wang, who is a world expert in the design and creation of energy-harvesting devices, has also pioneered electric bandages that stimulate wound-healing and a weight-loss implant that uses gentle electricity to trick the stomach into feeling full.
The hair-growth technology is based on a similar premise: Small devices called nanogenerators passively gather energy from day-to-day movements and then transmit low-frequency pulses of electricity to the skin. That gentle electric stimulation causes dormant follicles to “wake up”.
“Electric stimulations can help many different body functions,” says Wang. “But before our work there was no really good solution for low-profile devices that provide gentle but effective stimulations.”
Because the electric pulses are incredibly gentle and don’t penetrate any deeper than the very outermost layers of the scalp, the devices don’t seem to cause any unpleasant side effects. That’s a marked advantage over other baldness treatments, like the medicine Propecia, which carries risks of sexual dysfunction, depression and anxiety. What’s more, in side-by-side tests on hairless mice, the devices stimulated hair growth just as effectively as two different compounds found in baldness medicines.
The researchers have patented the concept with the Wisconsin Alumni Research Foundation, and they hope to move forward with human testing soon.